THE ONLY LICENSED TREATMENT FOR THE REDUCTION IN RECURRENCE OF OVERT HEPATIC ENCEPHALOPATHY (OHE) 1
When should TARGAXAN® be prescribed?
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| When to initiate TARGAXAN® | How long should TARGAXAN® be prescribed? | ||||
| After the first OHE episode to reduce the risk of further episodes. 1 | Expert clinical opinion suggests that people may continue to use TARGAXAN® until death or until liver transplant. 2 | ||||
How should you prescribe TARGAXAN®? 1
- Licensed dose: 550 mg (one tablet) twice a day.
- Each tablet contains 550 mg rifaximin-α.
- TARGAXAN® can be administered with or without food.
- No dosage adjustment needed in elderly patients and patients with renal or hepatic insufficiency.
- Use with caution in patients with severe hepatic impairment and in patients with MELD (Model for End-Stage Liver Disease) score >25.
- Use with caution in patients with impaired renal function.
TARGAXAN® Tolerability 1
Common adverse reactions are dizziness, headache, depression, dyspnoea, upper abdominal pain, abdominal distension, diarrhoea, nausea, vomiting, ascites, rashes, pruritus, muscle spasms, arthralgia and peripheral oedema. 1
Click here for a more detailed look at TARGAXAN® tolerability
UK/XIF5/0719/0522 DOP: October 2019