The only licensed treatment for the reduction in recurrence of overt hepatic encephalopathy (OHE)1
Evidence supporting TARGAXAN® 550mg treatment in the UK & Republic of Ireland:
Go to Pivotal Trial Data
Pivotal Trial Data
Go to Long-term Data
Long-term Data
Go to Real world evidence
Real world evidence
Go to National guidelines
National guidelines
The impact of hepatic encephalopathy (HE)2
Hepatic encephalopathy is a major complication of cirrhosis.2
Approximately 50% of people with cirrhosis will develop clinically apparent hepatic encephalopathy at some stage after diagnosis - the risk being around 5-25% within 5 years.2
Hospital admissions are common and inpatient stays often prolonged. The presence of hepatic encephalopathy is associated with a significant increase in mortality; survival after the first episode is 42% at 1 year and 23% at 3 years.2
What are the potential benefits of TARGAXAN® therapy?
Adverse event reporting
United Kingdom
The Yellow Card Scheme is run by the Medicines and Healthcare products Regulatory Agency (MHRA) and Commission on Human Medicine (CHM).
The scheme is used to collect information from health professionals and patients on suspected adverse drug reactions (ADRs). The continued success of the Yellow Card Scheme depends on your willingness to report suspected adverse drug reactions.
Both health professionals and patients can submit information through the Yellow Card website.
Adverse events should be reported. Reporting forms and information can be found at www.mhra.gov.uk/yellowcard.
Republic of Ireland
Healthcare professionals are asked to report any suspected adverse reactions via HPRA Pharmacovigilance, Earlsfort Terrace, IRL – Dublin 2;
Tel: +353 1 6764971; Fax: +353 1 6762517; Website: www.hpra.ie; Email: medsafety@hpra.ie.
You can also report to Norgine directly on Tel: 01895 826606 or Email: medinfo@norgine.com.
UK/XIF5/0719/0519 DOP: October 2019
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In submitting your email, you are giving permission for Norgine to contact you about your query. Your details will not be used for any other purpose.
Under the General Data Protection Regulation 2016 (EU) 2016/679, we have a legal duty to protect any personal information we collect from you.
Please refer to our policies page for further information.